Neocutis JOURNEE- Day Cream SPF 30+, 1 oz

Product Description: JOURNEE is the only Day Cream that combines PSP technology with antioxidants and broad spectrum UVA/UVB SPF 30+ sun protection. JOURNEE is the most complete Day Cream and combines many benefits in one single product.

Size: 1 fl oz

Benefits:
- Simultaneously addresses visible signs of chronological, photo-aging and premature skin aging
- Smoothes fine lines and wrinkles
- Guards against premature aging
- Nurtures post-procedural skin
- Protects from free radicals
- Helps prevent sun damage
- Revitalizes skin
- Ideal for all skin types.

About PSP: Years of research enabled the bio-engineering of Processed Skin Proteins (PSP). PSP is a naturally balanced mixture of essential skin nutrients including growth factors, interleukines, antioxidants and matrix proteins such as collagen.

Instructions: Apply JOURNE in the morning or follow the recommendations of your dermatologist. In the evening, use NEOCUTIS Bio-restorative Skin Cream or Bio-Gel Bio-restorative Hydrogel.

Ingredients:
Active ingredients...Purpose
Octinoxate 7.5%......Sunscreen
Zinc Oxide 7.3%......Sunscreen

Inactive ingredients: Water, Caprylic/Capric Triglyceride, Hydrogenated C6-14 Olefin Polymers, Hexyldecanol, Glycerin, Glyceryl Stearate, PEG-100 Stearate, Potassium Cetyl Phosphate, Hydrogenated Palm Glycerides, Microcrystalline Cellulose, Camelia Sinensis Extract, Silica, Cutaneous Lysate, Sodium Ascorbyl Phosphate, Tocopheryl Acetate, Squalane, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polyhydroxystearic Acid, Steareth-21, Melanin, Cetearyl Alcohol, Sodium Hyaluronate, Polysorbate 60, Triethoxycaprylsilane, Disodium EDTA, Xanthan Gum, Styrene/Acrylates Copolymer, Phenoxyethanol, Methylparaben, Ethylparaben, Propylparaben

Research Study *
PSP helps to improve the appearance of aged skin by providing human growth factors and cytokines for cells. PSP was shown to increase human dermal fibroblast viability as assessed by the MTT assay. The MMT assay is a standard assay based on the measurement of dehydrogenase enzyme activity in the mitochondria; the cells' power sources.
Recent research emphasizes that skin aging is characterized by a decline in cellular energy metabolism, which is mainly caused by detrimental changes in mitochondrial function. 1 The changes seem to be predominantly mediated by oxidative stress generated by solar ultraviolet radiation, air pollutants, or occurring as consequence of inflammation or as by-product of mitochondrial respiration, especially during aging. 2 This suggests that human skin cells being energetically recharged may be markedly protected against a variety of cellular stress conditions occurring during daily life, what may consequently prevent premature skin aging and skin damage.

1 J Invest Dermatol 2005, 124: 443-252
2 J Biomed Sci 1997, 4: 319-326
* Data obtained from www.neocutis.com
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